The use of plant protection machinery should deal with pesticides, and most pesticides are highly toxic substances, so in use, we must pay attention to the safety of operators, but also should prevent plant phytotoxicity and pollution of the environment. First of all, operators must be familiar with the nature of pesticides, strictly abide by the operating procedures. Do not run out of the pesticide shall be stored in a safe place, can not leave, to avoid misuse, harm people and livestock. Secondly, when spraying, we should control the dosage according to the growth period of crops, diseases and insect pests, and select the application time and air flow to improve the efficacy. Third, medical equipment after use should be cleaned after drying and then stored in the warehouse or in the garage.